zipper(noun, verb) noun1. a fastener for locking together two toothed edges by means of a sliding tabSimilar word(s): zipDefinition categories: man–made, fastener, fastening, fixing, holdfast verb1. close with a zipperSimilar word(s): zipDefinition categories: contact, fasten, fix, secureSentences with zipper as a verb:- He zippered his sweater against the cold.- This Fall jackets are zippered.