refractory
adjective
1. not responding to treatment
- a refractory case of acne
Similar word(s): intractable, stubborn
2. temporarily unresponsive or not fully responsive to a process or stimulus
- the refractory period of a muscle fiber
Similar word(s): unresponsive
3. stubbornly resistant to authority or control
- a refractory child
Similar word(s): disobedient, fractious, recalcitrant