1. causing irritation or annoyance
- nettlesome paperwork
2. easily irritated or annoyed
- not the least nettlesome of his countrymen
Sentences with nettlesome as an adjective:
- My poison ivy rash is very nettlesome.
- The task of proving Fermat’s “last” theorem remains nettlesome.
- Be careful what you say to him; he's a nettlesome fellow.