1. With the source or provenance of or at.

- This wine comes from France.  I got a letter from my brother

2. With the origin, starting point or initial reference of or at.

- He had books piled from floor to ceiling.  He left yesterday from Chicago.  Face away from the wall!

3. (mathematics, now uncommon) Denoting a subtraction operation.

- 20 from 31 leaves 11.

4. With the separation, exclusion or differentiation of.

- An umbrella protects from the sun.  He knows right from wrong.