1. giving careful attention to detail; hard to please; excessively concerned with cleanliness

- a fastidious and incisive intellect

- fastidious about personal cleanliness

Similar word(s): choosey, choosy, dainty, nice, overnice, prissy, squeamish, finical, finicky, fussy, particular, picky, meticulous, pernickety, persnickety, refined, tidy

2. having complicated nutritional requirements; especially growing only in special artificial cultures

- fastidious microorganisms

Similar word(s): exacting