1. indicating opposition or resistance

Similar word(s): negative, counter

2. characterized by antagonism or antipathy

- slaves antagonistic to their masters

Similar word(s): hostile, antipathetic, antipathetical

3. arousing animosity or hostility

- his antagonistic brusqueness

- Europe was antagonistic to the Unites States

Similar word(s): alienating

4. used especially of drugs or muscles that counteract or neutralize each other's effect

Similar word(s): antacid, antiphlogistic, incompatible

5. incapable of harmonious association

Similar word(s): incompatible